One Medical - Midtown 42nd Bryant Park
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Primary Care Doctor's Office in New York, NY Bryant Park

Our Bryant Park office offers exceptional primary care for adults of all ages, including seniors on Medicare. We focus on building real relationships with patients and using technology to simplify every aspect of getting care. And we’re not just here for when you’re sick or injured. We can also help you meet physical and mental health goals, manage chronic illnesses, and live a happier, healthier life. Plus, you can expect improved coordination of specialty care through our affiliation with Mount Sinai Health System. Think of us as your home for healthcare.

Same/next-day appointments available

Book online, no membership needed. Appointments are billed to you or your insurance; copays or deductibles may apply.

489 5th Avenue

3rd Floor

New York , NY 10017

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Contact us:

Office Hours:

Mon–Fri: 8AM–6PM
Sat–Sun: Closed
RN Hours: Monday through Friday 9am-12pm & 1pm-4pm (ages 18+)

Lab Hours:

Mon: 10AM–6PM
Tue: 8AM–6PM
Wed, Fri: 8AM–5:30PM
Thu: 8AM–4:30PM
Sat–Sun: Closed
****EARLY LAB CLOSURE 3/20/25 AT 4:30 PM****

Information

Public Transportation

Nearby Subway Stations
  • B, D, F, M, 7 to Bryant Park
  • 4, 5, 6 to Grand Central
  • 1, 2, 3 to Times Square
NYC MTA Home Page

Additional Information

Our Midtown - 42nd Street office is at 489 Fifth Avenue, across the street from Bryant Park and the New York Public Library. Our doctor's office is also directly next to Orvis Clothing Store.

Unfortunately, bikes are not allowed inside the building at this time.

No appointment needed if coming in during walk-in lab hours to fill a lab order that has already been ordered.

Our services

Think of us as your home for healthcare — your go-to for preventive care like physicals and screenings and your first stop when something feels off.

Frequently asked questions